Research Projects

Research Projects

MESuSIE

MESuSIE is a software for multi-ancestry fine-mapping. This work is in Press in Nature Genetics titled “MESuSiE enables scalable and powerful multi-ancestry fine-mapping of causal variants in genome-wide association studies”. The software can be found here. We also provided detailed instruction and analysis example here, and a web application here. Download paper here

GECKO

GECKO is a software for genetic correlation estimation. The work was published in PLOS GENETICS titled “Accurate genetic and environmental covariance estimation with composite likelihood in genome-wide association studies”. GECKO can be download here with detailed example and descriptions. Download paper here

Collaborative Projects

OMR

Mendelian randomization under the omnigenic architecture. Download paper here

PWAS

Proteome-wide association studies for blood lipids and comparison with transcriptome-wide association studies. Download paper here